Seminar on imaging applications in research including clinical aspects with a focus on neuroscience
Type of class Seminar
Offered by Medical Neurosciences
Instructor PD Dr. Andreas Wunder
Schedule Department of Experimental Neurology, Bonhoefferweg 3, Charité Campus Mitte, Seminar Room (R. 01 002)
Location Wednesdays 17:30 - 19:45, starting on June 01 2011, 8 Sessions
Contact PD Dr. Andreas Wunder ()
Target audience MSc and PhD, open to all neuroscience programs
ECTS points 2
Course material
Learning Outcome
Modern imaging technologies such as computed tomography (CT), magnetic resonance tomography (MRT), nuclear imaging methods (positron emission tomography = PET; single photon counting computed tomography = SPECT), and optical imaging technologies (fluorescence and bioluminescence imaging) play an important role to evaluate physiological and pathophysiologi-cal processes non-invasively in research and clinical settings. The goal of the seminar is to understand how these technologies work in principle (without details), how they can be applied to answer biological questions in animal disease models, and how these technologies are applied in clinical settings. Furthermore, the participants will be trained to work in autonomous working groups and to present scientific topics.
Structure
The seminar consists of eight sessions:
Session 1–4: Introduction to the seminar and comprehensible overview of the field. The participants will be divided into 3 working groups (CT/MRT group, SPECT/PET group, optical imaging group) according to their main interest. Each working group will elaborate two imaging modality on the basis of 3–4 scientific publications (some of them are listed below) and will present their findings to the other participants in the following sessions (Session 5–6). The content of the last 2 sessions is flexible.
Readings
Mandatory
- Garcia-Alloza M et al. Techniques for brain imaging in vivo. Neuromolecular Med. 2004;6:65–78
- Lythgoe MF et al. Neuroimaging of animal models of brain disease. Br Med Bull 2003;65:235–57
- Jacobs AH et al. Human gene therapy and imaging in neurological diseases. Eur J Nucl Med Mol Imaging. 2005;32 Suppl 2:S358–383.
- Cherry SR. In vivo molecular and genomic imaging: new challenges for imaging physics. Phys Med Biol 2004;49:R13-R48
Further
(see attached PDF document)